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Reishi Mushroom Extract

Our Organic Reishi (Ganoderma lucidum) Extract capsules provide an easily accessible way for you to experience the awesome power of this potent medicinal mushroom, known for millennia as a ‘miraculous king of herbs’!1

  • £29.99

About Reishi mushrooms

Our Organic Reishi (Ganoderma lucidum) Extract capsules provide an easily accessible way for you to experience the awesome power of this potent medicinal mushroom, known for millennia as a ‘miraculous king of herbs’!1

We are massively proud of the quality of our Organic Reishi Extract capsules which are made using a purified water-based extract taken from the fruiting bodies of organically grown Reishi mushrooms. This process is the most environmentally friendly extraction method and leaves the beneficial bio-active compounds intact whilst supercharging their concentration for our optimally purified capsules. Whilst formulating our Organic Reishi Extract capsules, we wanted to be sure that we were making a product that really delivers a punch and accordingly, our capsules are lab-verified to contain more than 60% polysaccharides and 25% β-Glucans. The specific content of these bio-active compounds was of the greatest importance to us as scientific research has shown us that they are responsible for the amazing health-promoting effects of the Reishi mushroom2. We then encapsulate a massive 500mg of our extracted organic Reishi powder into vegan HPMC capsules, providing you with a convenient way to benefit from the power of Reishi!

Recent research has shown that the Reishi mushroom could optimise health in many ways, with the potential to enhance your immune system, protect your liver and heart, reduce inflammation, act as a powerful antioxidant, aid healthy sleep and provide an anti-tumour and anti-diabetic effect1! Given that the Reishi mushroom has been used for more than 4000 years to treat a wide range of conditions in traditional medicines and is now receiving its well-earned recognition as a superfood, it’s definitely worth considering our Organic Reishi Extract Capsules if you are looking to enhance your health and wellbeing!

Reishi mushrooms: Three Key Facts


Reishi was described as an ‘immortality’ tonic in ancient Chinese medical texts, and whilst this may a contentious claim, it does positively impact a wide range of mechanisms known to slow aging. It has also been shown to extend lifespan in animals at least, so it would certainly be worth considering as an aid to youthful aging!


Reishi or ‘Lingzhi’ has been revered in traditional Chinese medicine due to the belief that it can promote health and longevity. Recent scientific research suggests that it does indeed have potent health-promoting effects, with the power to enhance our immune system, reduce inflammation, and protect the liver and cardiovascular system!3


Our Organic Reishi Extract is taken only from the fruiting bodies of the mushroom (where the beneficial bio-active compounds are most concentrated). Each capsule contains 500mg of our Organic Reishi Extract and has a lab certified content of more than 60% polysaccharides and 25% β-Glucans. These are the key bioactive compounds within the Reishi mushroom responsible for its incredible health-promoting effects, so you can rest assured that you are getting the best quality Reishi extract.

Why you should consider supplementing with Reishi mushrooms


Anti-aging benefits: Many studies have shown that Reishi is packed full of bio-active compounds with strong antioxidant activities which may provide a protective effect against the chronic diseases of aging. The antioxidant power of Reishi has also been found to limit the production of reactive oxygen species which if left unchecked, could in the long-term, increase cellular damage and accelerate aging. Recent studies have shown that Reishi can significantly extend the lifespan of C. elegans and traditionally, Reishi was hailed as an ‘immortality’ tonic. Though it’s unlikely that you’ll live forever; it’s certainly possible that you’ll live better for longer!

Help support your liver and cardiovascular system: The Reishi mushroom has been shown improve several bio-markers known to be associated with cardiovascular disease risk and can prevent heart damage in a variety of disease models. Research has shown that Reishi may also aid liver protection; preventing injury of liver cells through a range of biochemical mechanisms and helping to treat established liver damage.

Boost your immune system: The Reishi mushroom, and in particular, its polysaccharide content (as found concentrated in our Organic Reishi Extract capsules) has been found to have a strong immunomodulatory effect, meaning that they have the potential to positively affect our immune system enabling its optimal functioning.

Improve your sleep and fight fatigue: Reishi has been shown to have the power to decrease fatigue and improve mental wellbeing. It is also commonly reported to enhance sleep quality and duration so try our Organic Reishi Extract capsules for yourself and see if you can benefit from the doubled-up effect of a great night’s sleep and reduced fatigue!

What is a Reishi mushroom?


Reishi (Ganoderma lucidum) and known as ‘Lingzhi’ or ‘Mannentake’ is a medicinal mushroom with a long history in Far Eastern traditional medicines for its purported healing properties. According to beliefs over 2000 years ago, the Reishi mushroom was not only revered for its beneficial effects on health and longevity but was also hailed as a source of immortality5! Its importance was highlighted in ‘The Divine Farmer’s Materia Medica ‘; a well-respected pharmacopeia from the Qin dynasty (221-206 BC) and its image is frequently found in Chinese art over the past 2000 years6. Aside from it’s general use as a health-promoting tonic, it was also used traditionally to treat neurasthenia, insomnia, dizziness, heart disease, hepatitis and cancer7.

Due to its revered status in traditional Chinese medicine, the Reishi mushroom has been scientifically studied in depth over the past 30 years and has been found to have a wide range of diverse health benefits. In particular, there has been strong evidence that Reishi can enhance the immune system, decrease inflammation, protect the heart and liver, aid sleep and act as a potent antioxidant1,8!

The Reishi mushroom contains a diverse array of beneficial bioactive compounds including polysaccharides, β-glucans, nucleotides, sterols, peptides and numerous vitamins, minerals, and trace elements9. From these compounds, the polysaccharide (which includes the β-glucans) content of Reishi is key to its awesome health enhancement properties10. Research has shown that Reishi’s polysaccharides have numerous positive biological activities, including antioxidant, anti-fatigue, prolonging life, anti-tumour, anti-inflammatory, immunomodulation and reducing blood lipids and sugars10. With this in mind, we maximised the polysaccharide and β-glucan content of our Organic Reishi Extract capsules so that we could formulate the best quality, efficacious product backed by scientific research!

What are the potential benefits of consuming Reishi mushrooms?

Excessive inflammation is known to increase our risk of developing a wide variety of chronic diseases. In addition, the term ‘inflammaging’ has recently been coined to refer to the negative impact that inflammation can have on our aging; causing us to age excessively beyond our chronological age. Though acute inflammation is normally a beneficial response to what our body perceives as a stress, excessive or chronic inflammation is often caused through an inappropriate response by our immune system or its continuous activation, past the point where it is beneficial. Luckily though, the Reishi mushroom could prove a valuable ally towards reducing excessive inflammation!

A review of scientific research found that the Reishi mushroom can act as a potent anti-inflammatory through a variety of mechanisms11. It has been shown to inhibit the activation of pro-inflammatory immune cells (stopping inflammatory cells) and decrease the production of pro-inflammatory cytokines (signalling molecules). Another study specifically tested the impact of a Reishi polysaccharide extract on total inflammation in a mice model and found an impressive 57% reduction in inflammation12! Lastly, it is worth mentioning that allergic reactions are often a case of excessive and inappropriate inflammation and Reishi has also shown promise in helping prevent allergic reactions, specifically in relation to the symptoms of asthma, contact dermatitis and multiple sclerosis11.

Our immune system is our defence system against invading viruses, bacteria and other pathogens. When our immune system is working effectively, it also keeps surveillance internally to detect and kill pre-cancerous cells before they can develop into cancers or tumours. Unfortunately, with age but also accelerated by the constant barrage of exposure to environmental toxins we receive, our immune system can deteriorate and lose its function. This is where immunomodulating compounds such as Reishi can have a great benefit on our health; the term ‘immunomodulating’ being used to describe the ability of Reishi to optimise our immune system to the needs of our body.

One review study analysed several different scientific experiments and found that polysaccharides extracted from Reishi do have a potent immunomodulatory effect, with the ability to exert a significant, positive impact on our immune cells, including B lymphocytes, T lymphocytes, NK cells, macrophages and dendritic cells13. Another, more recent study found that Reishi’s polysaccharides protected the spleen and thymus (the organs where we develop our immune cells) and led to an increase in the production of new white blood cells and lymphocytes (types of blood cells involved in our immune system)14. These studies have primarily been conducted in animals or cells and so the findings must be considered with a degree of caution, but the results do suggest that consuming Reishi certainly has the possibility to help enhance your immune system!

Our cardiovascular system includes our heart and blood vessels and unfortunately, cardiovascular diseases are one the major causes of morbidity and mortality around the world. However, Reishi has shown promise in its ability to maintain our cardiovascular system in optimal health! A review of the scientific research found that Reishi can have a positive effect on cholesterol (reducing total cholesterol and LDL, whilst increasing HDL), decrease blood pressure and prevent heart damage in a range of different disease models15.

Despite most studies being conducted on isolated cells or animals, there was an interesting experiment conducted on a group of 26 human patients with either mild hypertension (high blood pressure) or hyperlipidemia (excessive fats in the blood)16. This is very useful as both markers are often indicators of risk for developing heart disease later in life. The study found that Reishi might actually have a mild antidiabetic effect and that it also improved the hyperlipidemia (reducing total triglycerides and improving the ‘healthy’ HDL count). This is a really interesting study and shows that Reishi can have a direct impact on our health! It is worth bearing in mind too, that this study took place over a 12-week period and the patients were given 1.44g of a Reishi extract split between the morning and evening, so this would be the same dose as taking just 3 of our Organic Reishi Extract capsules a day.

The Reishi mushroom has been used traditionally to help liver function and there has been quite a wide range of scientific evidence suggesting that it could be effective in helping to protect the liver. When Reishi extracts were tested in different animal studies, scientists found that the Reishi helped protect against liver injury and had an anti-hepatitis B virus activity17.

Due to these promising results, Reishi was used in a controlled human clinical trial with patients suffering from chronic hepatitis B and showed a massive impact in reducing their hepatitis B burden over a 6-month period. The authors of the study concluded that Reishi was well tolerated and active against the hepatitis B virus18. Further support for the liver protective effects of Reishi come from a more recent study, which gave a group of 42 healthy, human participants either a 225mg capsule of Reishi extract (less than half the dose of one of our capsules) or a placebo each day for 6 months before swapping over. After taking the Reishi for 6 months, there was a significant increase in antioxidant activity in the liver, decreased liver stress and most impressively, a reversal from mild fatty liver conditions to normal conditions in some of the patient19. As you may know, the liver is a hugely important organ, with one of its main roles being to constantly detoxify harmful compounds so they don’t build up in our body. Keeping your liver as healthy as possible pays dividends for your overall health and along with a healthy diet and lifestyle, our Organic Reishi Extract capsules could be just the aid you need to ensure your liver stays working in 100% order!

Many people self-report one of the greatest benefits of Reishi is the sleep enhancement it gives them. Our team at Phytobalance has used Reishi for many years and also experienced the same improvements in sleep quality, however, as part of the Phytobalance ethos, we would only suggest a benefit if it was supported by scientific research and so set out the examine what had been found!

One study found that total sleep time and non-rapid eye movement sleep was significantly increased in rats after just 3 days of supplementation with a Reishi extract20 whilst another very recent study also found that Reishi increased sleep time and also decreased sleep latency (time take to fall asleep) in mice21. They showed that this was likely due to an increase in levels of the sleep-promoting neurotransmitter 5-HTP in the brain which was dependant on the gut bacteria of the mice. An interesting example of the important synergy we have with our gut microbiome, potentially showing that Reishi is beneficial for them, which in turn, enables them to provide a greater benefit for us!

In addition to its benefits on sleep, there is the possibility that Reishi might be beneficial towards combatting stress and fatigue. One study found that in patients suffering from neurasthenia, over an 8-week period, daily supplementation with a 5.4g Reishi extract with 25% polysaccharide content (equivalent to 4-5 of our capsules) caused a significant reduction in fatigue and improvement in wellbeing22. Another study also found an improvement in physical wellbeing, decreased fatigue and less anxiety/depression, this time in a group of breast cancer patients suffering from cancer related fatigue23. These studies highlight a real possibility of the benefits that Reishi can bring to mental wellbeing and reduced fatigue, however, it must be remembered that these studies were done with small groups of patients and there has also been conflicting evidence in other groups of patients.

Reishi was renowned in traditional medicines for enhancement of health and longevity and was even hailed as a key to immortality!

When testing the effect of different interventions, model organisms which share similar genes or characteristics with us are often used. One benefit of this is that the effect over the whole lifespan can be studied very quickly, rather than waiting 80+ years to see whether the effect in humans. The C. elegans nematode worm is one of these ‘model organisms’ and Reishi has been shown to extend their median lifespan substantially; from 17.3 days to 23.5 days24! This study found that this lifespan extension was as a result of multiple biological pathways but significantly due to increased anti-oxidation. A second recent study also found a similar effect, this time Reishi increased median lifespan from 13 days to 18.5 days (actually more then the renowned lifespan extending drug Rapamycin)25! This study found that this lifespan extension was due to increased stress resilience and autophagy in the worms, both of which are pathways we share as humans.

Now admittedly, we are very different from the C. elegans nematode and these studies must be considered with this in mind. However, health benefits seen in ‘model organisms’ in response to different interventions often translate to benefits for human (these similarities are why we use model organisms to test effects of interventions), so in light of Reishi’s ancient repute as a longevity tonic, it would definitely be worth considering it as an addition to your anti-aging protocol!

How to use:
Powder - Take 1-2g daily as required. A 1g daily serving has been shown to have a range of clinical effects in scientifc research. The minimum recommended daily dose is 1g, however, up to 2g per day could provide greater benefits.
Capsules - Take 2 capsules daily as required. Our capsules have been formulated to the equivalent doses used in scientifc research which have been shown to have a range of clinical effects. The minimum recommended daily dose is 2 capsules, however, up to 4 capsules per day could provide greater benefits.

How to store: Store in ziplock bag (or an airtight resealable container) in a cool, dry place and out of the reach of young children. Please reseal bag after use. Once opened, we recommend consuming this product within 6 months to ensure that maximum nutritional benefits are retained.

Powder - Organic Reishi (Ganoderma lucidum) extract powder derived from the fruiting body,
Capsules - Organic Reishi (Ganoderma lucidum) extract powder derived from the fruiting body, HPMC capsule shell (hydroxypropyl methylcellulose).

Warning: This product is a food supplement and should not be used as replacement for a varied, balanced diet and healthy lifestyle. The recommended dose should not be exceeded. Please consult your GP before using this product if you are trying to conceive, pregnant, nursing, have existing medical conditions or are taking any prescription medication. Not suitable for children and adolescents under 18 years.


1 El Sheikha, A.F., 2022. Nutritional Profile and Health Benefits of Ganoderma lucidum “Lingzhi, Reishi, or Mannentake” as Functional Foods: Current Scenario and Future Perspectives. Foods, 11(7), p.1030.

2 Lu, J., He, R., Sun, P., Zhang, F., Linhardt, R.J. and Zhang, A., 2020. Molecular mechanisms of bioactive polysaccharides from Ganoderma lucidum (Lingzhi), a review. International journal of biological macromolecules, 150, pp.765-774.

3 Batra, P., Sharma, A.K. and Khajuria, R., 2013. Probing Lingzhi or Reishi medicinal mushroom Ganoderma lucidum (higher Basidiomycetes): a bitter mushroom with amazing health benefits. International journal of medicinal mushrooms, 15(2).

4 Cui, X.Y., Cui, S.Y., Zhang, J., Wang, Z.J., Yu, B., Sheng, Z.F., Zhang, X.Q. and Zhang, Y.H., 2012. Extract of Ganoderma lucidum prolongs sleep time in rats. Journal of ethnopharmacology, 139(3), pp.796-800.

5 Nahata, A., 2013. Ganoderma lucidum. A Potent Medicinal Mushroom with Numerous Health Benefits Pharmaceut Anal Acta, 4(10), p.1000e159.

6 Bishop, K.S., Kao, C.H., Xu, Y., Glucina, M.P., Paterson, R.R.M. and Ferguson, L.R., 2015. From 2000 years of Ganoderma lucidum to recent developments in nutraceuticals. Phytochemistry, 114, pp.56-65.

7 Jong, S.C. and Birmingham, J.M., 1992. Medicinal benefits of the mushroom Ganoderma. Advances in applied microbiology, 37, pp.101-134.

8 Babu, P.D. and Subhasree, R.S., 2008. The sacred mushroom “Reishi”-a review. American-Eurasian Journal of Botany, 1(3), pp.107-110.

9 Sanodiya, B.S., Thakur, G.S., Baghel, R.K., Prasad, G.B.K.S. and Bisen, P.S., 2009. Ganoderma lucidum: a potent pharmacological macrofungus. Current pharmaceutical biotechnology, 10(8), pp.717-742.

10 Lu, J., He, R., Sun, P., Zhang, F., Linhardt, R.J. and Zhang, A., 2020. Molecular mechanisms of bioactive polysaccharides from Ganoderma lucidum (Lingzhi), a review. International journal of biological macromolecules, 150, pp.765-774.

11 Bhardwaj, N., Katyal, P. and K Sharma, A., 2014. Suppression of inflammatory and allergic responses by pharmacologically potent fungus Ganoderma lucidum. Recent Patents on Inflammation & Allergy Drug Discovery, 8(2), pp.104-117.

12 Joseph, S., Sabulal, B., George, V., Antony, K.R. and Janardhanan, K.K., 2011. Antitumor and anti-inflammatory activities of polysaccharides isolated from Ganoderma lucidum. Acta pharmaceutica, 61(3), pp.335-342.

13Xu, Z., Chen, X., Zhong, Z., Chen, L. and Wang, Y., 2011. Ganoderma lucidum polysaccharides: immunomodulation and potential anti-tumor activities. The American journal of Chinese medicine, 39(01), pp.15-27.

14 Li, J., Gu, F., Cai, C., Hu, M., Fan, L., Hao, J. and Yu, G., 2020. Purification, structural characterization, and immunomodulatory activity of the polysaccharides from Ganoderma lucidum. International journal of biological macromolecules, 143, pp.806-813.

15 Meng, J. and Yang, B., 2019. Protective effect of Ganoderma (Lingzhi) on cardiovascular system. Ganoderma and Health, pp.181-199.

16Chu, T.T., Benzie, I.F., Lam, C.W., Fok, B.S., Lee, K.K. and Tomlinson, B., 2012. Study of potential cardioprotective effects of Ganoderma lucidum (Lingzhi): results of a controlled human intervention trial. British Journal of Nutrition, 107(7), pp.1017-1027.

17 Gao, Y., Huang, M., Lin, Z.B. and Zhou, S., 2003. Hepatoprotective activity and the mechanisms of action of Ganoderma lucidum (Curt.: Fr.) P. Karst.(Ling Zhi, Reishi mushroom)(Aphyllophoromycetideae). International Journal of Medicinal Mushrooms, 5(2).

18 Gao, Y., Zhou, S., Chen, G., Dai, X., Ye, J. and Gao, H., 2002. A phase I/II study of a Ganoderma lucidum (Curt.: Fr.) P. Karst.(Ling Zhi, Reishi Mushroom) extract in patients with chronic Hepatitis В. International Journal of Medicinal Mushrooms, 4(4).

19 Chiu, H.F., Fu, H.Y., Lu, Y.Y., Han, Y.C., Shen, Y.C., Venkatakrishnan, K., Golovinskaia, O. and Wang, C.K., 2017. Triterpenoids and polysaccharide peptides-enriched Ganoderma lucidum: a randomized, double-blind placebo-controlled crossover study of its antioxidation and hepatoprotective efficacy in healthy volunteers. Pharmaceutical biology, 55(1), pp.1041-1046.

20 Cui, X.Y., Cui, S.Y., Zhang, J., Wang, Z.J., Yu, B., Sheng, Z.F., Zhang, X.Q. and Zhang, Y.H., 2012. Extract of Ganoderma lucidum prolongs sleep time in rats. Journal of ethnopharmacology, 139(3), pp.796-800.

21 Yao, C., Wang, Z., Jiang, H., Yan, R., Huang, Q., Wang, Y., Xie, H., Zou, Y., Yu, Y. and Lv, L., 2021. Ganoderma lucidum promotes sleep through a gut microbiota-dependent and serotonin-involved pathway in mice. Scientific reports, 11(1), pp.1-14.

22 Tang, W., Gao, Y., Chen, G., Gao, H., Dai, X., Ye, J., Chan, E., Huang, M. and Zhou, S., 2005. A randomized, double-blind and placebo-controlled study of a Ganoderma lucidum polysaccharide extract in neurasthenia. Journal of medicinal food, 8(1), pp.53-58.

23 Zhao, H., Zhang, Q., Zhao, L., Huang, X., Wang, J. and Kang, X., 2012. Spore powder of Ganoderma lucidum improves cancer-related fatigue in breast cancer patients undergoing endocrine therapy: a pilot clinical trial. Evidence-Based Complementary and Alternative Medicine, 2012.

24 Cuong, V.T., Chen, W., Shi, J., Zhang, M., Yang, H., Wang, N., Yang, S., Li, J., Yang, P. and Fei, J., 2019. The anti-oxidation and anti-aging effects of Ganoderma lucidum in Caenorhabditis elegans. Experimental Gerontology, 117, pp.99-105.

25 Peng, H.H., Wu, C.Y., Hsiao, Y.C., Martel, J., Ke, P.Y., Chiu, C.Y., Liau, J.C., Chang, I.T., Su, Y.H., Ko, Y.F. and Young, J.D., 2021. Ganoderma lucidum stimulates autophagy-dependent longevity pathways in Caenorhabditis elegans and human cells. Aging (Albany NY), 13(10), p.13474.